Associations of adversity in childhood and risk factors for cardiovascular disease in mid-adulthood

Simple item page
dc.contributor.authorAnderson, Emma L. ,Fraser, Abigail , Caleyachetty, Ris, ; Hardy, Rebecca ,Lawlor, Debbie A. , & Howe, Laura D.
dc.date.accessioned2018-01-23T14:58:49Z
dc.date.available2018-01-23T14:58:49Z
dc.date.issued2018
dc.description.abstractStudies assessing associations of childhood psychosocial adversity (e.g. sexual abuse, physical neglect, parental death), as opposed to socioeconomic adversity, with cardiovascular disease (CVD) risk factors in adulthood are scarce. The aim of this study is to assess associations of various types of psychosocial adversity and cumulative adversity in childhood, with multiple CVD risk factors in mid-life. At study enrolment, women from the Avon Longitudinal Study of Parents and Children (N = 3612) retrospectively reported: lack of maternal care, maternal overprotection, parental mental illness, household dysfunction, sexual abuse, physical and emotional abuse, and neglect in childhood. Approximately 23 years later, body mass index (BMI), waist circumference, systolic and diastolic blood pressure, plasma glucose, insulin, triglycerides, low and high density lipoprotein cholesterol, C-reactive protein, carotid intima-media thickness (cIMT) and arterial distensibility were assessed (mean age 51 years). We examined associations of each specific type of psychosocial adversity and cumulative adversity with CVD risk factors. No specific type of psychosocial adversity was consistently associated with the CVD risk factors. There was evidence that a one standard deviation greater cumulative psychosocial adversity was associated with 0.51 cm greater waist circumference (95% confidence interval [CI]: 0.02 cm, 1.00 cm, p = 0.04) and a lower arterial distensibility, even after adjustment for age, ethnicity and childhood and adult socioeconomic position. We found no consistent evidence that any specific type of psychosocial adversity, or cumulative psychosocial adversity in childhood, is associated with CVD risk factors in adult women. (Author Abstract)en_US
dc.identifier.citationAnderson, Emma L. ,Fraser, Abigail , Caleyachetty, Ris, ; Hardy, Rebecca ,Lawlor, Debbie A. , & Howe, Laura D. (2018). Associations of adversity in childhood and risk factors for cardiovascular disease in mid-adulthood. Child Abuse & Neglect, 76, 138-148.en_US
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0145213417304106/pdfft?md5=6b57014bf5c58fbb7bb9512279bdacc8&pid=1-s2.0-S0145213417304106-main.pdf
dc.identifier.urihttp://hdl.handle.net/11212/3688
dc.language.isoenen_US
dc.publisherChild Abuse & Neglecten_US
dc.subjectchild abuseen_US
dc.subjectlong term effectsen_US
dc.subjecthealth effectsen_US
dc.subjectheart diseaseen_US
dc.subjecthypertensionen_US
dc.subjectweighten_US
dc.subjectrisk factorsen_US
dc.subjectresearchen_US
dc.subjectInternational Resourcesen_US
dc.subjectUnited Kingdomen_US
dc.titleAssociations of adversity in childhood and risk factors for cardiovascular disease in mid-adulthooden_US
dc.typeArticleen_US

Files

Collections

CALiO Collection of Resources