Disease burden of adverse childhood experiences across 14 states

dc.contributor.authorWaehrer, G. M., Miller, T. R., Silverio Marques, S. C., Oh, D. L., & Burke Harris, N.
dc.date.accessioned2020-02-05T15:48:19Z
dc.date.available2020-02-05T15:48:19Z
dc.date.issued2020
dc.description.abstractObjective To examine whether the relationship between Adverse Childhood Experiences (ACEs) and health outcomes is similar across states and persists net of ACEs associations with smoking, heavy drinking, and obesity. Methods We use data from the Behavioral Risk Factor Surveillance System for 14 states. Logistic regressions yield estimates of the direct associations of ACEs exposure with health outcomes net of health risk factors, and indirect ACEs-health associations via health risk factors. Models were estimated for California (N = 22,475) and pooled data from 13 states (N = 110,076), and also separately by state. Results Exposure to ACEs is associated with significantly higher odds of smoking, heavy drinking, and obesity. Net of these health risk factors, there was a significant and graded relationship in California and the pooled 13-state data between greater ACEs exposure and odds of depression, asthma, COPD, arthritis, and cardiovascular disease. Four or more ACEs were less consistently associated across states with cancer and diabetes and a dose-response relationship was also not present. There was a wide range across individual states in the percentage change in health outcomes predicted for exposure to 4+ ACEs. ACEs-related smoking, heavy drinking, and obesity explain a large and significant proportion of 4+ ACEs associations with COPD and cardiovascular disease, however some effect, absent of risk behavior, remained. Conclusions ACE’s associations with most of the health conditions persist independent of behavioral pathways but only asthma, arthritis, COPD, cardiovascular disease, and depression consistently exhibit a dose-response relationship. Our results suggest that attention to child maltreatment and household dysfunction, mental health treatment, substance abuse prevention and promotion of physical activity and healthy weight outcomes might mitigate some adverse health consequences of ACEs. Differences across states in the pattern of ACEs-health associations may also indicate fruitful areas for prevention.en_US
dc.identifier.citationWaehrer, G. M., Miller, T. R., Silverio Marques, S. C., Oh, D. L., & Burke Harris, N. (2020). Disease burden of adverse childhood experiences across 14 states. PloS one, 15(1), e0226134.en_US
dc.identifier.urihttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0226134
dc.identifier.urihttp://hdl.handle.net/11212/4589
dc.language.isoen_USen_US
dc.publisherPLoS Oneen_US
dc.subjectchild abuseen_US
dc.subjectresearchen_US
dc.subjectAdverse Childhood Experiences (ACE)en_US
dc.subjectlong term effectsen_US
dc.subjecthealth effectsen_US
dc.titleDisease burden of adverse childhood experiences across 14 statesen_US
dc.typeArticleen_US

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