Maternal depression during pregnancy and offspring depression in adulthood: role of child maltreatment

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dc.contributor.authorPlant, D. T., Pariante, C. M., Sharp, D., & Pawlby, S.
dc.date.accessioned2015-10-01T15:37:44Z
dc.date.available2015-10-01T15:37:44Z
dc.date.issued2015
dc.description.abstractBackground: Studies have shown that maternal depression during pregnancy predicts offspring depression in adolescence. Child maltreatment is also a risk factor for depression. Aims: To investigate (a) whether there is an association between offspring exposure to maternal depression in pregnancy and depression in early adulthood, and (b) whether offspring child maltreatment mediates this association. Method: Prospectively collected data on maternal clinical depression in pregnancy, offspring child maltreatment and offspring adulthood (18–25 years) DSM-IV depression were analysed in 103 mother–offspring dyads of the South London Child Development Study. Results: Adult offspring exposed to maternal depression in pregnancy were 3.4 times more likely to have a DSM-IV depressive disorder, and 2.4 times more likely to have experienced child maltreatment, compared with non-exposed offspring. Path analysis revealed that offspring experience of child maltreatment mediated the association between exposure to maternal depression in pregnancy and depression in adulthood. Conclusions: Maternal depression in pregnancy is a key vulnerability factor for offspring depression in early adulthood. (Author Abstract)en_US
dc.identifier.citationPlant, D. T., Pariante, C. M., Sharp, D., & Pawlby, S. (2015). Maternal depression during pregnancy and offspring depression in adulthood: role of child maltreatment. The British Journal of Psychiatry, 207(3), 213-220en_US
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555443/?report=reader
dc.identifier.urihttp://hdl.handle.net/11212/2539
dc.language.isoenen_US
dc.publisherThe British Journal of Psychiatryen_US
dc.subjectInternational Resourcesen_US
dc.subjectUnited Kingdomen_US
dc.subjectChild abuseen_US
dc.subjectresearchen_US
dc.subjectrisk factorsen_US
dc.subjectlong term effectsen_US
dc.titleMaternal depression during pregnancy and offspring depression in adulthood: role of child maltreatmenten_US
dc.typeArticleen_US

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